The Association of Ontario Health Centre’s Transformative Change Award recognizes leaders, innovators, collaborators and health champions who have been working at the forefront of transformative change helping us achieve the AOHC vision of the best possible health and wellbeing for everyone living in Ontario. On June 7, 2017, Parkdale Queen West Community Health Centre, Sandy Hill Community Health Centre, and South Riverdale Community Health Centre were recognized for their work in expanding harm reduction programs to include Supervised Injection Services. These services will undeniably save lives and help reduce risk factors that lead to infectious diseases. These efforts have helped shift the conversation around substance use and mental health, and enhanced the engagement in many communities towards transforming the landscape of harm reduction, drug policy and evidence-based practices.